Navigating Dual Diagnosis: Treating Schizophrenia and Substance Use Disorder

Medically reviewed by Anna Kravtsov, D.O.
Written by Rashida Ruwa
Posted on November 4, 2026

Key Takeaways

  • People living with both schizophrenia and a substance use disorder (SUD) can get treatment for both conditions at the same time, and sharing details about substance use with a healthcare team can help them build a plan that addresses both.
  • Having schizophrenia and a SUD, sometimes called a dual diagnosis or co-occurring disorders, can make each condition harder to manage on its own. Substance use can worsen psychotic symptoms like hallucinations and delusions, while some people may use substances to cope with symptoms, which can make it harder to tell what is driving a change in how someone feels.
  • If you or someone you care about is living with both conditions, talking openly with a healthcare provider about substance use, asking about integrated treatment options, and exploring support through therapy, peer groups, or a case manager can all be helpful steps to take.
  • View all takeaways

If you have both schizophrenia and a substance use disorder (SUD), you may wonder whether you can get treatment for both. Fortunately, you don’t have to choose between mental healthcare and SUD treatment. Telling your healthcare team about your substance use can help them build a treatment plan that addresses both conditions.

This guide explains what dual diagnosis treatment can involve, how to talk with your psychiatrist, and what to ask when you’re seeking care.

Understanding Dual Diagnosis

Healthcare providers use the term dual diagnosis when someone has a mental health condition, such as schizophrenia, along with a SUD. You may also hear this referred to as co-occurring disorders.

🗳️ Has your care team been helpful in treating both schizophrenia and substance use disorder?
Yes
No
I haven’t discussed both diagnoses with them yet

Having both schizophrenia and a SUD doesn’t necessarily mean that one caused the other. Substance use can occur before, after, or around the same time as schizophrenia symptoms, and it can sometimes be hard to tell which came first.

Certain factors may also play a role in either condition, including genetics, stress, and traumatic experiences. But these factors can affect people differently, so there may not be one clear reason why both conditions develop.

How Can the Conditions Affect Each Other?

Some people with schizophrenia use alcohol or drugs to help cope with hallucinations (seeing or hearing things that aren’t there), trouble sleeping, and medication side effects. This is referred to as “self-medication,” which is the practice of treating oneself with medication or substances without the guidance or prescription of a healthcare professional.

Substance use can also make schizophrenia more difficult to manage. It is linked to poorer treatment outcomes, can worsen psychotic symptoms, and can also make it harder to take medication as prescribed. Some substances can even cause psychosis.

When both conditions are present, it can be hard to tell what’s behind a change in symptoms. Some substances, and withdrawal from them, can cause hallucinations or delusions (strongly held false beliefs) that can look a lot like symptoms of schizophrenia.

Why People May Delay or Hide Substance Use Care

Many people with schizophrenia hold back about sharing their struggles with alcohol or drug use because they may worry about being judged by their healthcare team. Stigma can also make people less likely to seek or engage with psychiatric care.

Some people may worry that disclosing their substance use will affect their psychiatric treatment. But having schizophrenia doesn’t prevent someone from receiving treatment for substance use. Sharing details about which substances you use can help your psychiatrist make safer medication decisions.

Others worry that their substance use will become the main focus of their psychiatric care. SUD is a mental health condition, and knowing about your substance use can help your healthcare team consider treatment options for both conditions.

Integrated Treatment for Both Conditions

Dual diagnosis treatment can include several types of support, depending on your symptoms, substance use, medical history, and the care available where you live.

Coordinated Mental Health and Addiction Care

A dual-diagnosis program puts your schizophrenia and substance use disorder care under one healthcare team. That team may include a psychiatrist, an addiction specialist, a therapist, and a case manager.

When your healthcare team coordinates your care, they can consider your substance use alongside your medications, daily life, and physical health. This can make it easier to notice when one condition is affecting the other and adjust your care.

But if you receive mental health and addiction care through separate programs, ask whether your providers can share information with your permission to help coordinate care.

Medications

Medication may be part of treatment for schizophrenia, SUD, or both. Antipsychotic medications can help manage psychotic symptoms such as hallucinations and delusions.

Depending on the substance involved, other medications may ease withdrawal, reduce cravings, or lower the risk of returning to substance use. For opioid use disorder, approved medications include buprenorphine, methadone, and naltrexone.

However, some medication combinations can increase sedation or other risks, so it is best not to stop, start, or change a medication on your own. Ask your psychiatrist or substance use treatment provider how your medications can work together safely.

Therapy and Behavioral Support

Psychotherapy can help you build coping skills and give you strategies for managing substance use. Depending on your situation, treatment may include individual, family, or group therapy.

Approaches like cognitive behavioral therapy (CBT) can help you work toward reducing or stopping substance use. Motivational interviewing can help build your confidence to make changes and stay engaged in treatment.

Treatment doesn’t have to address every concern at once. Your healthcare team can help you choose what to work on first, and your plan can shift as you become more ready for change.

Peer, Family, and Community Support

Recovery doesn’t have to happen through medical appointments alone. Support groups can connect you with people who understand what it’s like to live with mental health and substance use challenges, which may help you feel less alone.

Groups like Dual Diagnosis Anonymous support people living with a dual diagnosis like schizophrenia and SUD. Other groups, such as Alcoholics Anonymous, focus on alcohol use. If a group isn’t a good fit, it’s OK to try another.

When you’re managing a dual diagnosis, family members or other trusted people can help you stay connected to your care. They may help you get to appointments, remember medications, notice changes in your symptoms, or manage day-to-day tasks.

A case manager can also help coordinate appointments, connect you with housing or community resources, and address barriers that make treatment harder to access, such as transportation or insurance.

Talking With a Psychiatrist About Substance Use

Talking openly about substance use can be hard, especially if you’re worried about how it could affect your psychiatric care.

You can start by sharing a few details that can help your psychiatrist understand what’s happening. For instance:

Which substances you use, such as alcohol, cannabis, stimulants, or opioids
How often and how much you use
When you last used them
Whether your use has recently increased or decreased
Whether you notice changes in your symptoms, sleep, or mood after using or stopping

You don’t have to downplay your substance use because you’re afraid of being judged. You can tell your psychiatrist what’s happening and ask which treatment options are available.

If your healthcare provider doesn’t offer treatment for both conditions, you can ask about a referral to a program that does.

Questions To Ask About Treatment Access

If you’re looking for treatment for schizophrenia and SUD, consider asking:

Do you offer integrated treatment for SUD and schizophrenia?
How will my mental health and substance use care be coordinated?
What treatment options are available for my specific substance use?
How will you check that my medications are safe to take together?
What therapy, peer support, or other services are available?
Can a case manager help with transportation, housing, or other barriers to care?
What happens if I’m not ready to stop using a substance completely?
How often will we review my symptoms and treatment plan?
What should I do if my symptoms get worse?

Asking these questions can help you understand your options without having to make every treatment decision at once.

How Caregivers Can Support Someone With Both Conditions

Supporting someone with schizophrenia and an SUD can bring worry, frustration, and uncertainty, especially when you want to help but can’t make decisions for them. But you can offer support while respecting their choices.

For instance, you can ask about their substance use without blaming or shaming them. Ask about their goals rather than telling them what to do, and respect their decisions about their care, even when you disagree.

The LEAP method (listen, empathize, agree, partner) can help when the person you’re caring for doesn’t feel ready to seek treatment. You can also offer help with everyday tasks, such as rides to appointments or help finding treatment programs.

You can pay attention to changes in their mood, behavior, substance use, or symptoms, as well. If you notice changes that concern you, encourage them to talk with their healthcare team and offer to help them get care.

If someone is in immediate danger or may have overdosed, seek emergency medical help. In the United States, call 911 or call or text 988 Suicide & Crisis Lifeline for crisis support.

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